Short-Acting Beta Agonists (SABA)

Respiratory

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Examples

salbutamol (albuterol)terbutaline

Prefix / Suffix: -ol

Physiology

β2 receptors in the lungs cause bronchodilation when stimulated. In asthma, bronchoconstriction narrows the airways. SABAs rapidly relax airway smooth muscle.

Mechanism of Action

They stimulate β2 receptors in the lungs, causing rapid bronchodilation.

Indications

  • Acute asthma attack
  • Bronchospasm relief
  • Rescue therapy

Side Effects / Adverse Effects

  • Tachycardia (β1 stimulation at higher doses)
  • Tremors (β2 stimulation in skeletal muscle)
  • Palpitations
  • Hypokalemia (shift of potassium into cells)

Contraindications

  • Severe tachycardia
  • Use cautiously in cardiac patients

Nursing Considerations

  • Use as rescue inhaler, not for maintenance (frequent use indicates poor asthma control)
  • Assess respiratory status before and after use (improvement confirms effectiveness)
  • Monitor heart rate (risk of tachycardia, especially with repeated doses)
  • Teach correct inhaler technique (ensures drug reaches lungs)
  • If patient uses it more than 2 times/week, report (indicates need to step up therapy)

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Disclaimer: PharmPal Nurse is for education only and is not medical advice. Do not use it to diagnose, treat, prescribe, or make patient-care decisions; always verify with current drug references, your instructor, facility policy, and a licensed provider. In emergencies, call local emergency services.