Long-Acting Beta Agonists (LABA)

Respiratory

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Examples

salmeterolformoterol

Prefix / Suffix: -ol

Physiology

β2 receptor stimulation leads to prolonged bronchodilation, helping keep airways open over time.

Mechanism of Action

They stimulate β2 receptors, causing sustained bronchodilation for up to 12–24 hours.

Indications

Long-term asthma control
COPD maintenance therapy

Side Effects / Adverse Effects

Tachycardia (β1 spillover effect)
Tremors
Headache

Contraindications

Acute asthma attack (not for rescue)

Nursing Considerations

Never use alone in asthma — must be combined with ICS to reduce risk of asthma-related death
Not for acute attacks (slow onset compared to SABA)
Ensure patient has a rescue inhaler (SABA) available (for emergencies)
Monitor frequency of use (overuse may indicate poor control)

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Disclaimer: PharmPal Nurse is for education only and is not medical advice. Do not use it to diagnose, treat, prescribe, or make patient-care decisions; always verify with current drug references, your instructor, facility policy, and a licensed provider. In emergencies, call local emergency services.