Cholesterol Absorption Inhibitors

Cardiovascular

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Examples

ezetimibe

Prefix / Suffix: No consistent suffix

Physiology

Cholesterol is absorbed from the intestine into the bloodstream. Reducing absorption lowers blood cholesterol levels.

Mechanism of Action

They block cholesterol absorption in the small intestine.

Indications

Hyperlipidemia
Often combined with statins

Side Effects / Adverse Effects

Diarrhea (GI effect)
Abdominal pain
Elevated liver enzymes (when combined with statins)

Contraindications

Severe liver disease

Nursing Considerations

Monitor liver function (especially when combined with statins)
Assess lipid levels (to evaluate effectiveness)
Educate on diet modification (enhances drug effectiveness)

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